Drug intelligence / Profile preview

SA100

Development stage
Phase 1
Lead developer
Stanford University
Administration
Oral
01

Overview

SA100 is an orally administered herbal therapeutic developed at Stanford University for the treatment of ulcerative colitis (UC). The drug was initiated by Julie Saiki, a PhD student in Chemical and Systems Biology, and developed in collaboration with Stanford's inflammatory bowel disease program. SA100 is intended for patients with mild-to-severe UC, particularly those who have failed 5-aminosalicylic acid (5-ASA) treatment but have not yet progressed to more intensive immunosuppressive or biologic therapies. It has been evaluated in a Phase 1b open-label, dose-escalation study to assess safety and preliminary efficacy over an 8-week treatment period. While the treatment is based on traditional medicine practices used for centuries, its specific active botanical components and biological targets remain undisclosed.

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