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saccharomyces cerevisiae
- Development stage
- Phase 2
- Modality
- Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral, Intradermal, Epicutaneous
01
Overview
Saccharomyces cerevisiae is a species of fungus (yeast) widely used in food production (baking and brewing), biotechnology, and medicine. In clinical settings, it is primarily used as a probiotic to restore or maintain healthy gut flora and prevent or treat various forms of diarrhea—including antibiotic-associated diarrhea and traveler's diarrhea—by competing with pathogenic microorganisms in the gastrointestinal tract. The strain Saccharomyces cerevisiae var. boulardii is specifically manufactured for medicinal use as a probiotic agent[5][6][8]. Its mechanism of action involves restoration of intestinal microbiota balance and inhibition of pathogen adhesion to the gut lining[8]. It can also be used as an allergenic extract for diagnostic testing in allergy clinics[1][2][4]. Genetically engineered strains are employed in the production of recombinant pharmaceuticals such as insulin and vaccines[6].
- Brand names
- Saccharomyces Cerevisiae P
- Other names
- baker's yeastbrewer's yeastbudding yeastS. cerevisiae
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