Drug intelligence / Profile preview

safe bovine heparin

Development stage
Preclinical
Lead developer
Heptech
Modality
Small Molecules
Administration
Intravenous, Subcutaneous
01

Overview

Safe Bovine Heparin (SBH) is a bovine-derived heparin anticoagulant being developed by Heptech as a sustainable and safe alternative to porcine-derived heparin. Heparin is a glycosaminoglycan that exerts its anticoagulant effect by binding to antithrombin III (ATIII), which significantly accelerates ATIII's inhibition of thrombin (Factor IIa) and Factor Xa. SBH is intended to address supply chain vulnerabilities and cultural/religious restrictions associated with porcine heparin while maintaining a high safety profile through rigorous sourcing and purification processes to mitigate risks such as bovine spongiform encephalopathy (BSE). The drug is currently in preclinical development as a replacement for standard porcine heparin in anticoagulation therapy.

Other names
Safe Bovine HeparinSBHbovine heparin
02

Targets

F2 (Thrombin)F10 (Factor Xa)ATIII (Antithrombin III)

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