Drug intelligence / Profile preview

SagaPro

Development stage
Unknown
Lead developer
SagaMedica
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

SagaPro is a botanical dietary supplement derived from the leaves of *Angelica archangelica* (Icelandic angelica), a medicinal herb with a long history of use in Iceland. Developed by SagaMedica ehf., it is primarily used to manage nocturia (frequent nighttime urination) and lower urinary tract symptoms (LUTS) often associated with benign prostatic hyperplasia (BPH). The supplement is believed to work by relaxing the smooth muscle cells of the bladder and urethra, a process potentially mediated by bioactive constituents such as leukotriene inhibitors, flavonoids, and polyphenols. Clinical studies, including randomized, double-blind, placebo-controlled trials, have evaluated its efficacy in improving nocturnal bladder capacity and reducing void frequency in men aged 45 and older.

Brand names
SagaPro
Other names
Angelica archangelica leaf extract
02

Targets

CYSLTR1 (Cysteinyl-leukotriene type 1 receptor)

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