salacia chinensis extract

Salacia chinensis extract is a botanical extract derived from the root and stem of the Salacia chinensis plant, a medicinal herb traditionally used in Ayurvedic medicine. The extract is notable for its **α-glucosidase inhibitory activity**, which slows carbohydrate digestion and glucose absorption, resulting in **suppression of postprandial (after-meal) blood glucose and insulin spikes**[1][2][3][4]. Mechanistic studies show SCE also **inhibits pancreatic lipase**, reducing fat absorption, and at higher concentrations can inhibit HMG-CoA reductase[1]. SCE modulates gene expression relevant to lipid metabolism (upregulating C/EBP alpha, downregulating ACC, PPARG, SCD-1)[1]. Human clinical trials in healthy subjects and patients with type 2 diabetes have shown dose-dependent improvement in **postprandial blood glucose, insulin response, and HbA1c**[2][3]. Additional effects observed in animal and in vitro models include **antiobesity**, **antioxidant**, **anticaries**, **antiulcer**, **hypoglycemic**, and skin lightening activities[1][5]. SCE is used as a **dietary supplement** for diabetes, metabolic syndrome, and obesity[9]. The main active phytochemicals identified in Salacia chinensis include triterpenes, phenolic compounds, glycosides, mangiferin, and salacinol-related compounds[5][7].

Other names

SCESalacia chinensisSalacia chinensis Linn.