salbutamol + bromhexine + menthol

Salbutamol + bromhexine + menthol is a fixed-dose combination (FDC) medication primarily used to treat respiratory conditions characterized by bronchospasm and excessive, viscous mucus. Salbutamol is a short-acting beta-2 adrenergic receptor agonist that promotes bronchodilation by increasing intracellular cAMP levels, which leads to the relaxation of bronchial smooth muscle. Bromhexine acts as a mucolytic and secretolytic agent; it increases the production of serous mucus in the respiratory tract and facilitates the breakdown of acid mucopolysaccharide fibers in thick phlegm, making it less viscous and easier to expectorate. Menthol is included for its cooling and soothing properties, which are mediated through the activation of TRPM8 receptors in the upper respiratory tract, providing relief from throat irritation and a mild antitussive effect. This combination is commonly prescribed as an oral syrup for patients suffering from productive cough associated with asthma, bronchitis, or chronic obstructive pulmonary disease (COPD).

Brand names

Asal-BMSalmaplon-BMMucocureS-BromSaliac-BM

Other names

salbutamol, bromhexine, and menthol combinationsalbutamol/bromhexine/menthol