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Salcol
- Development stage
- Unknown
- Lead developer
- Amdis Healthsciences
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Oral
01
Overview
Salcol is a nutraceutical product developed and marketed by Amdis Healthsciences, primarily indicated for the management of joint pain and osteoarthritis. Its primary active ingredient is **undenatured collagen type II (UC-II)**, a protein derived from chicken sternum cartilage. Unlike denatured collagen, UC-II maintains its biological activity and works through a mechanism known as oral tolerance. Upon ingestion, it interacts with Peyer's patches in the gut-associated lymphoid tissue (GALT), triggering the production of regulatory T cells (Tregs) that migrate to the joints and release anti-inflammatory cytokines like IL-10 and TGF-beta. This process helps to suppress the immune-mediated destruction of articular cartilage and promotes joint repair and mobility.
- Brand names
- Salcol
- Other names
- Undenatured Collagen Type IIUC-II
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