Drug intelligence / Profile preview

Saliactive

Development stage
Unknown
Lead developer
Mucosa Innovations
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Saliactive is a proprietary oral care composition developed by Mucosa Innovations, consisting of a combination of olive oil, betaine, and xylitol. It is designed to address oral dysbiosis and gingivitis by promoting a state of eubiosis within the oral microbiome, maintaining physiological pH, and reducing inflammation. Olive oil provides antioxidant properties, betaine acts as an osmoprotectant to hydrate and protect the oral mucosa, and xylitol inhibits the growth of cariogenic bacteria such as *Streptococcus mutans*. The composition is delivered via specialized oral hygiene products, such as the YOTUEL microbiome toothpaste, and has been evaluated in clinical trials for its ability to modulate the oral microbiome and reduce pro-inflammatory markers.

Brand names
SaliactiveYOTUEL microbiome toothpaste
Other names
olive oil + betaine + xylitol

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