Drug intelligence / Profile preview

saline + ketoprofen + paracetamol

Development stage
Unknown
Modality
Small Molecules
Administration
Intravenous, Oral, Intramuscular, Subcutaneous
01

Overview

This product is a **combination drug** consisting of three components: saline (sterile sodium chloride solution), ketoprofen, and paracetamol. **Ketoprofen** is a non-steroidal anti-inflammatory drug (NSAID) that acts by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, reducing the production of prostaglandins responsible for pain, inflammation, and fever. **Paracetamol** (also known as acetaminophen) is an analgesic and antipyretic that works primarily in the central nervous system to inhibit prostaglandin synthesis, providing pain and fever relief. **Saline** is used as a vehicle or diluent for intravenous or other parenteral administration, ensuring isotonicity and compatibility with body fluids. The combination of ketoprofen and paracetamol is known to provide more effective analgesia with a faster onset compared to either agent alone and is used for acute pain management, often in the postoperative setting[1][2]. Combination products including both ketoprofen and paracetamol are marketed in some countries, sometimes with additional excipients or vehicles such as saline[5][2].

02

Targets

COX-3 (Mitochondrially encoded cytochrome c oxidase subunit 3)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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