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saline placebo
- Development stage
- Unknown
- Lead developer
- Stanford University
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Saline placebo refers to the inactive control treatment used in the CALBLOC clinical trial (NCT05027048) sponsored by Stanford University. This Phase 3, randomized, double-blind trial investigates the use of intravenous calcium chloride to prevent uterine atony and postpartum hemorrhage (PPH) during intrapartum cesarean delivery. The saline placebo is administered as an intravenous infusion to the control group to provide a baseline for comparing the efficacy and safety of calcium chloride in reducing quantitative blood loss and improving uterine tone in high-risk patients. As a placebo, it contains no active pharmacological ingredients and is used to maintain the blinding of the study, allowing researchers to isolate the therapeutic effects of calcium chloride from the effects of the infusion process itself.
- Other names
- saline infusionplacebo
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