Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
saline solution + Osteonil Mini
- Development stage
- Unknown
- Lead developer
- TRB Chemedica
- Modality
- Small Molecules
- Administration
- Intraarticular
01
Overview
saline solution + Osteonil Mini is a combination treatment approach investigated for the management of thumb carpometacarpal (CMC) joint osteoarthritis, also known as rhizoarthritis. The procedure involves an initial joint lavage (washing) using a physiologic saline solution to remove inflammatory debris and mediators from the joint space, followed by an intra-articular injection of Osteonil Mini. Osteonil Mini is a viscosupplement formulation containing 10 mg of sodium hyaluronate and 5 mg of mannitol in a 1 mL solution. Sodium hyaluronate acts as a lubricant and shock absorber to restore the rheological properties of the synovial fluid, while mannitol serves as an antioxidant to protect the hyaluronic acid from oxidative degradation by free radicals. This specific treatment protocol has been studied by the University of Sao Paulo General Hospital, particularly in patients with metabolic comorbidities such as obesity and hypertension.
- Brand names
- Osteonil Mini
- Other names
- sodium hyaluronate + mannitol + saline solutionLavage with physiologic saline solution and Osteonil Mini
Beyond the preview
Go deeper on saline solution + Osteonil Mini.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on saline solution + Osteonil Mini.