saline solution isotonic 0.9% NaCl

Saline solution isotonic 0.9% NaCl (commonly referred to as normal saline or physiological saline) is a sterile, isotonic solution of sodium chloride in water. In the context of the VENLID clinical trial (NCT06354816), it is utilized as a pharmacologically inert placebo comparator to evaluate the efficacy of a 10% lidocaine spray (Xylocaine) in reducing pain associated with the insertion of a peripheral intravenous catheter (PIVC) in female adults. The solution is administered topically via a spray dispenser (0.5 ml or 5 pulses) to the planned insertion site with a 2-minute exposure time. Because it is isotonic with human blood, it has no active pharmacological properties or specific biological targets in this context, serving purely as an inactive control.

Other names

0.9% sodium chlorideisotonic salinenormal salinephysiological salinephysiological saline solutionsaline solutionsodium chloride 0.9%