saline solutions

Saline solutions, specifically intraocular saline, are used as an inert control or placebo in clinical trials to maintain scientific rigor. In a prospective interventional randomized controlled study conducted by Cairo University, saline is injected intracamerally at the conclusion of phacoemulsification in diabetic patients. This intervention serves as a volume-matched comparator to evaluate the safety and efficacy of intracameral dexamethasone in reducing corneal endothelial cell loss and preventing corneal endothelial decompensation. As a sterile sodium chloride solution, it lacks active pharmacological properties but is essential for assessing the relative benefit of therapeutic interventions in ophthalmic surgery.

Other names

Saline Solutions, Intraocularsterile sodium chloride solutionintracameral saline