saline spray

Saline spray is an inert solution, typically consisting of sodium chloride in water, used as a placebo control in clinical trials. In the context of a Phase 4 randomized, double-blind, placebo-controlled trial conducted at the University of Pennsylvania (NCT01925469), it was utilized as a comparator to benzocaine spray to evaluate pain management during hysterosalpingogram (HSG). HSG is a radiographic procedure used to assess the uterine cavity and fallopian tubes in women undergoing infertility evaluation. As a placebo, saline spray lacks active pharmacological properties and serves to establish a baseline for efficacy and safety assessments. The study found no significant difference in pain relief between the benzocaine and saline spray groups during or after the procedure.

Other names

saline solution spray