Drug intelligence / Profile preview

salix alba bark

Development stage
Phase 2
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Salix alba bark (white willow bark) is a plant-derived extract from the Salicaceae family used in some over-the-counter products and traditional medicine. Its primary active constituent is salicin—a compound metabolized to salicylic acid in the body—which provides analgesic and anti-inflammatory effects similar to aspirin. Willow bark has been used for centuries to treat pain conditions such as back pain and osteoarthritis; clinical trials have shown moderate efficacy for lower back pain and dysmenorrhea but less so for arthritis. It is not an approved pharmaceutical drug but is available as a dietary supplement or herbal remedy. The mechanism of action involves inhibition of prostaglandin synthesis via cyclooxygenase enzyme blockade due to its conversion into active metabolites[1][2][3][4][5][8].

Brand names
assalix
Other names
willow barkwhite willow barksalicis cortexsalix albabai liu barksalix alba (willow) bark extractsalix alba stem barksalix alba stem bark dry extractsalix vitellina barkwhite willow extract
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

Beyond the preview

Go deeper on salix alba bark.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on salix alba bark.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call