Drug intelligence / Profile preview

Salmonella Newport Bacterial Extract

Development stage
Unknown
Lead developer
Vaxxinova
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Salmonella Newport Bacterial Extract is a specialized veterinary vaccine designed to protect cattle against salmonellosis caused by *Salmonella enterica* serovar Newport. It is the first vaccine to utilize Siderophore Receptor and Porin (SRP) technology, which focuses on the bacterial cell wall proteins responsible for iron uptake. By immunizing animals with these purified SRP proteins, the vaccine stimulates the production of antibodies that bind to and block these essential channels. Because iron is a limiting and vital nutrient for bacterial replication and pathogenesis, this blockade effectively starves the bacteria, leading to reduced colonization, decreased fecal shedding, and mitigated clinical symptoms in both dairy and beef cattle. The vaccine is primarily indicated for use in healthy dairy and beef cattle and is administered via subcutaneous injection.

Brand names
Salmonella Newport Bacterial Extract
Other names
Salmonella Newport bacterinSalmonella Newport SRP vaccineSalmonella Newport Bacterial Extract, Siderophore Receptors and Porins
02

Targets

S. enterica (Salmonella enterica)OmpC (Outer membrane porin C)

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