salophen iron chelate

Salophen iron chelate is a synthetic coordination compound consisting of an iron ion complexed with the tetradentate Schiff base ligand salophen (N,N′-bis(salicylidene)-1,2-phenylenediamine). It is classified as a small molecule and has been investigated primarily as an experimental agent. Salophen iron chelate acts as a metal-chelating agent and has potential therapeutic applications in treating conditions related to iron overload and possibly cancer. Its mechanism involves binding to free or excess iron ions in biological systems through strong coordination bonds formed by the ligand's nitrogen and oxygen donor atoms. This sequestration of free iron may reduce oxidative stress or modulate cellular processes dependent on available metal ions. The compound is not approved for clinical use but remains of interest for research into novel chelation therapies and anti-cancer strategies[1][4][7].

Other names

2,2'-[1,2-phenylenebis(nitrilomethylidene)]bis[phenolato]](2-)-N,N',O,O']-iron[2,2'-{benzene-1,2-diylbis[(nitrilo-kappaN)methylylidene]}diphenolato(2-)-kappaO]iron(2+)Q27467790Q-27467790Q 27467790