Drug intelligence / Profile preview

salvia miltiorrhiza extract

Development stage
Unknown
Modality
Classical Binding Small Molecules → Small Molecules
Administration
Oral, Intravenous
01

Overview

Salvia miltiorrhiza extract is a botanical preparation derived from the root of the plant *Salvia miltiorrhiza* Bunge (commonly known as Danshen). It has been used extensively in traditional Chinese medicine for cardiovascular and other health conditions. The extract contains multiple bioactive compounds including water-soluble phenolics (such as salvianolic acids), liposoluble tanshinones (notably tanshinone IIA), and polysaccharides. Its mechanisms of action are diverse and include antioxidant effects; anti-inflammatory activity; vasodilation; antiplatelet aggregation; improvement of microcirculation; immunomodulation; hepatoprotection; nephroprotection; and possible calcium channel antagonism. Clinical studies have shown potential benefits in coronary artery disease (including angina pectoris), acute ischemic stroke, myocardial infarction recovery by reducing reperfusion injury and improving endothelial function[2][5]. Recent trials also suggest efficacy for lower urinary tract symptoms in men[6] and inflammatory bowel disease[7]. The quality of clinical evidence varies due to heterogeneity in preparations and study design.

Brand names
DanshenDuofensuanyan
Other names
Salvia miltiorrhiza rootChinese Sage RootChinese SalviaChinese Salvia RootDan Shen (Salvia Miltiorrhiza)Danshen RootFuzheng Huayu Component Radix Salvia MiltiorrhizaeRadix Salvia MiltiorrhizaeRed Sage RootRed-root Sage RootSalvia Miltiorrhiza Root ExtractSalvia Miltiorrhiza Root With RhizomeSalvia Miltiorrhizae RootSalvia RootSalviae Miltiorrhizae Radix Et Rhizoma
02

Targets

Sucrase-Isomaltase

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