Drug intelligence / Profile preview

Salymet

Development stage
Unknown
Lead developer
Pharmedic
Modality
Small Molecules
Administration
Topical
01

Overview

Salymet is a topical analgesic cream developed and manufactured by the Vietnamese pharmaceutical company Pharmedic. It is a combination product containing methyl salicylate, menthol, and camphor, formulated for the symptomatic relief of musculoskeletal pain, including arthritis, rheumatism, neuralgia, and muscle strains. Methyl salicylate acts as a counter-irritant and a precursor to salicylic acid, which inhibits cyclooxygenase enzymes to reduce prostaglandin synthesis. Menthol and camphor function as topical analgesics by stimulating sensory nerves to produce cooling and warming sensations, effectively masking underlying pain through a counter-irritant mechanism. The product is marketed as an over-the-counter (OTC) generic treatment in Vietnam.

Brand names
Salymet
Other names
Salymet cream
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPV3 (Transient receptor potential vanilloid subtype 3)

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