Drug intelligence / Profile preview

Samarin

Development stage
Unknown
Lead developer
Berlin Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Samarin is an over-the-counter antacid and fruit salt product primarily used to treat heartburn and acid indigestion. It is a combination product typically containing sodium bicarbonate, citric acid, tartaric acid, and sodium carbonate. When dissolved in water, these ingredients react to form a buffering solution. In recent clinical research, Samarin has been investigated for a novel indication in obstetrics: the treatment of labor dystocia. The rationale is that bicarbonate acts as a lactic acid buffer; by reducing the accumulation of lactate in the myometrium (reflected by amniotic fluid lactate levels), it may enhance uterine contractile performance and reduce the necessity for emergency caesarean sections.

Brand names
Samarin
Other names
Sodium bicarbonateFruit salt

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