San-Huang Gu-Ben Zhi-Ke

San-Huang Gu-Ben Zhi-Ke (SHGBZK) is a Traditional Chinese Medicine (TCM) herbal formula developed by Beijing Hospital for the treatment of stable chronic obstructive pulmonary disease (COPD). It is specifically indicated for patients presenting with the lung-spleen Qi deficiency syndrome. The formula typically contains herbs such as Astragalus membranaceus (Huangqi), Scutellaria baicalensis (Huangqin), and Polygonum cuspidatum (Huzhang), which collectively represent the 'San-Huang' (Three Yellows) components. SHGBZK is designed to 'consolidate the root' (Gu-Ben), referring to strengthening the body's vital energy, and 'relieve cough' (Zhi-Ke). Clinical studies have demonstrated that SHGBZK can significantly improve respiratory symptoms, exercise capacity (as measured by the 6-minute walk test), and health-related quality of life. Evidence also suggests it may reduce the frequency of acute exacerbations and improve lung function in specific high-risk subgroups, such as patients with frequent exacerbations or high symptom burdens.

Brand names

Sanhuang Guban Zhike

Other names

San-Huang Gu-Ben Zhi-Ke formulaSanhuang Guben Zhike