Sangzhu Yangzheng Yin

Sangzhu Yangzheng Yin is a Traditional Chinese Medicine (TCM) herbal formula developed primarily as an adjuvant therapy for gastrointestinal cancers, including colorectal and gastric cancer. The formula is designed to "nourish the upright qi" (Yangzheng) and address the TCM syndrome of "spleen deficiency and dampness-heat," which is commonly observed in patients undergoing chemotherapy. Its primary therapeutic components typically include *Morus alba* (Mulberry leaf/Sang Ye) and *Atractylodes macrocephala* (Bai Zhu), alongside other supportive herbs like *Astragalus* and *Poria*. Research indicates that Sangzhu Yangzheng Yin exerts its effects by modulating the gut microbiota, inhibiting pro-inflammatory signaling pathways such as TLR4/NF-κB, and enhancing systemic immune function. Clinically, it is utilized to improve quality of life, reduce chemotherapy-induced toxicities (such as hand-foot syndrome and gastrointestinal distress), and potentially inhibit tumor progression by altering the tumor microenvironment.

Other names

桑术养正饮Sangzhu Yangzheng Decoction