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Sanqi Tongfeng
- Development stage
- Preclinical
- Lead developer
- Kunming Institute of Nephrology
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Sanqi Tongfeng is a Traditional Chinese Medicine (TCM)-derived therapeutic developed by the Kunming Institute of Nephrology, specifically indicated for the treatment of acute gouty arthritis. The formulation is primarily based on extracts from *Panax notoginseng* (Sanqi), which contains bioactive notoginsenosides and ginsenosides. These components exert potent anti-inflammatory and analgesic effects by inhibiting the NLRP3 inflammasome pathway and reducing the production of pro-inflammatory cytokines such as interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α). By modulating the inflammatory response triggered by monosodium urate crystals, Sanqi Tongfeng aims to rapidly alleviate the intense pain, redness, and swelling associated with acute gout flares. It is often utilized as a hospital preparation in clinical settings specializing in nephrology and metabolic diseases.
- Brand names
- Sanqi Tongfeng
- Other names
- Sanqi Tongfeng Granules三七痛风颗粒Sanqi Tongfeng Ke-li
02
Targets
NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)IL1B (Interleukin-1 beta)
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