Drug intelligence / Profile preview

santalum album heartwood

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Inhalation, Topical
01

Overview

Lignum Santali Albi is the pharmaceutical name for the dried heartwood of *Santalum album* L. (Family Santalaceae), commonly known as White Sandalwood. It is a significant botanical drug in Traditional Chinese Medicine (TCM) and Ayurveda, primarily valued for its volatile oil content, which is rich in sesquiterpene alcohols such as alpha-santalol and beta-santalol. Pharmacologically, it is used to treat conditions related to Qi stagnation and blood stasis, particularly in the cardiovascular and gastrointestinal systems. It is a key component in several traditional formulations, including Kuanxiong (KX) Aerosol and Guanxin Suhe Wan (GSW), which are indicated for the treatment of angina pectoris and coronary heart disease. Research indicates that its active constituents possess anti-inflammatory, antioxidant, and vasorelaxant properties, and it is also used for its sedative and aromatic qualities in various therapeutic contexts.

Other names
lignum santali albiWhite SandalwoodTan XiangSandalwood heartwoodSantalum album
02

Targets

GABRA1 (Gamma-aminobutyric acid type A receptor alpha 1 subunit)

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