Drug intelligence / Profile preview

Sanwei Qingzhi granules

Development stage
Phase 2
Lead developer
Baokang Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Sanwei Qingzhi granules is a traditional Chinese medicine (TCM) formulation developed by the Baokang Hospital of Tianjin University of Traditional Chinese Medicine. It is formulated as oral granules and is being evaluated in clinical trials for the treatment of mild hyperlipidemia.

Other names
Sanwei Qingzhi granule
02

Targets

FABP4 (Fatty acid-binding protein 4)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)LC3 (Microtubule-associated proteins 1A/1B light chain 3B)JNK (Mitogen-activated protein kinase kinase kinase family)MMP9 (Matrix metalloproteinase-9)NOS2 (Nitric Oxide Synthase 2)PPARA (Peroxisome proliferator-activated receptor alpha)PPARG (Peroxisome proliferator-activated receptor gamma)mTOR (Mammalian target of rapamycin kinase)

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