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Sanye Tongzhiqing Tablets
- Development stage
- Phase 2
- Lead developer
- Tianjin University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Sanye Tongzhiqing Tablets is an investigational Traditional Chinese Medicine (TCM) formulation developed by Tianjin University of Traditional Chinese Medicine. It is primarily being evaluated for the treatment of type 2 diabetes mellitus, specifically targeting patients with the "phlegm-turbidity and blood stasis" pattern according to TCM diagnostics. The drug is designed to improve glycemic control and metabolic parameters, and it has been studied in Phase 2 clinical trials in China as both a monotherapy for treatment-naive patients and as an add-on therapy for those inadequately controlled on metformin. As a botanical-based product, its therapeutic effects are likely derived from the synergistic action of multiple active components found in its constituent herbs, which are intended to regulate lipid metabolism and insulin sensitivity.
- Other names
- Sanye Tongzhiqing Pian
02
Targets
Sucrase-IsomaltasePIM2 (Proto-oncogene serine/threonine-protein kinase Pim2)PPARG (Peroxisome proliferator-activated receptor gamma)
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