Drug intelligence / Profile preview

Sanzi Fang

Development stage
Preclinical
Lead developer
Nanjing University of Chinese Medicine
Administration
Oral
01

Overview

Sanzi Fang (SZF) is a Traditional Chinese Medicine (TCM) herbal compound that has been investigated for its potential in the prevention and treatment of colorectal adenoma (CRA). Research, primarily in preclinical mouse models, suggests that SZF exerts its therapeutic effects by modulating the intestinal flora and improving colorectal metabolic profiles. It has been observed to increase beneficial gut bacteria and decrease harmful ones, as well as normalize various colorectal metabolites. This traditional formula is being explored for its ability to prevent the progression of CRA to cancer.

Other names
SZF三子方三子方颗粒剂模拟剂Sanzi formula
02

Targets

EGFR (Epidermal growth factor receptor)ERBB2 (Erb-b2 receptor tyrosine kinase 2)MMP2 (Matrix metalloproteinase-2)MMP9 (Matrix metalloproteinase-9)

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