Drug intelligence / Profile preview

Sanzi Huangshi No. 2

Development stage
Unknown
Lead developer
Shanghai Municipal Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Sanzi Huangshi No. 2 is a Traditional Chinese Medicine (TCM) formulation developed by the Shanghai Municipal Hospital of Traditional Chinese Medicine and Shanghai University of Traditional Chinese Medicine. It is primarily investigated for the treatment of low-risk myelodysplastic syndrome (MDS). The formulation is typically administered as pills and is often evaluated in combination with thalidomide to assess its efficacy in improving hematological parameters and managing disease progression. As a TCM product, its therapeutic effects are thought to involve multi-target modulation of the hematopoietic microenvironment and immune regulation, aimed at improving blood cell counts and reducing the risk of transformation in MDS patients.

Brand names
Sanzi Huangshi No. 2
Other names
Sanzi Huangshi No. 2 pillsSanzi Huangshi Er Hao
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))BAX (Apoptosis regulator BAX)IL-6 (Interleukin 6)

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