Drug intelligence / Profile preview

Sanzi Huangshi Wan

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Sanzi Huangshi Wan, also known as Sanzi-huangshi pill (SHP), is a traditional Chinese medicine formulation containing Realgar, Radix pseudostellariae, Semen cuscutae, and Ligustrum lucidum. It is an arsenic-containing medicine being investigated as an adjuvant therapy for lower-risk myelodysplastic syndrome (MDS). Preliminary studies suggest that Sanzi Huangshi Wan may improve erythrocytopenia, thrombocytopenia, and quality of life in patients with lower-risk MDS, potentially by regulating apoptosis and histone acetylation. The formulation is prepared as traditional pills and administered orally.

Brand names
Sanzi Huangshi No.1 Pill
Other names
Sanzi-huangshi pillSHPSanzi Huangshi No. 1 Pill

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