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saposhnikoviae radix
- Development stage
- Unknown
- Administration
- Oral, Topical
01
Overview
Saposhnikoviae Radix, commonly known as Fang Feng, is a traditional Chinese herbal medicine derived from the dried root of *Saposhnikovia divaricata* (Turcz.) Schischk. It is characterized by its content of bioactive chromones, including prim-O-glucosylcimifugin and cimifugin, as well as coumarins and polyacetylenes. The herb is traditionally used to treat "wind-damp" conditions, including rheumatoid arthritis, headaches, and spasms. Modern pharmacological studies highlight its anti-inflammatory, analgesic, and antioxidant properties. It has been investigated in clinical trials, often as a component of multi-herb formulas like Tong Xie Yao Fang, for the treatment of gastrointestinal disorders such as irritable bowel syndrome (IBS).
- Other names
- fang fengSaposhnikovia divaricata rootRadix Saposhnikoviaedivaricate saposhnikovia rootSaposhnikovia divaricata (Turcz.) Schischk.
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NOS2 (Nitric Oxide Synthase 2)NF-κBTNFA (Tumor necrosis factor alpha (soluble))
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