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SAR113244 is a biologically engineered monoclonal antibody developed by Sanofi for the treatment of systemic lupus erythematosus (SLE), an autoimmune disease. It acts as an antagonist of the C-X-C chemokine receptor type 5 (CXCR5), targeting overactive immune cells implicated in lupus pathogenesis. The drug was designed for subcutaneous injection. Development was discontinued after early-phase clinical trials.
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