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SAR402663 is an investigational drug developed by Sanofi for the treatment of neovascular (wet) age-related macular degeneration (nAMD). It is currently being evaluated in a Phase 1/2 clinical trial as a one-time intravitreal injection, with the aim of improving vision and reducing disease progression in adults with nAMD. The precise mechanism of action for SAR402663 has not been disclosed or remains undefined. The drug is considered a new molecular entity and represents a novel approach within eye disorder therapies. Clinical studies involve dose escalation and expansion phases, followed by long-term follow-up to assess safety and durability of effect.
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