saratin

Saratin is a **recombinant protein** originally isolated from the saliva of the medicinal leech (*Hirudo medicinalis*)[4]. It is a **12 kDa protein** that acts as an **inhibitor of von Willebrand factor (vWF)**, thereby **inhibiting platelet-collagen interactions** and **reducing platelet aggregation**[2][4]. Saratin has shown anti-inflammatory and anti-platelet effects and is being investigated for indications such as **antithrombotic therapy**, prevention of **platelet adhesion**, and **intimal hyperplasia** after vascular interventions[2][3][4]. It has also been evaluated preclinically for use in ophthalmic surgery to prevent post-surgical fibrosis[3].