Drug intelligence / Profile preview

sardine oil

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Sardine oil is a natural marine lipid derivative, primarily composed of omega-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It is widely recognized as a dietary supplement and has been investigated for its various health-promoting properties. These include its antioxidant capabilities, its role in modulating lipid profiles (decreasing triglycerides and LDL, increasing HDL), and its potential to influence inflammatory processes through its conversion into specialized pro-resolving lipid mediators (SPMs). Research also explores its application in improving hematological parameters, promoting angiogenesis, and macrophage polarization in wound healing, and its oxidative stability when incorporated into novel delivery systems.

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