Drug intelligence / Profile preview

saroglitazar sulfoxide

Development stage
Unknown
Lead developer
Zydus Lifesciences
Modality
Small Molecules
Administration
Oral
01

Overview

Saroglitazar sulfoxide is an active metabolite of the drug saroglitazar. Saroglitazar itself is a novel dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist. Saroglitazar sulfoxide possesses pharmacological activity, though its activity is marginally lower than that of the parent drug. It is quantitatively measured during the clinical development of saroglitazar.

02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)VEGFR2 (Vascular endothelial growth factor receptor 2)PPARA (Peroxisome proliferator-activated receptor alpha)EGFR (Epidermal growth factor receptor)ERBB2 (Erb-b2 receptor tyrosine kinase 2)

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