Drug intelligence / Profile preview

sarpodipil

Development stage
Phase 1
Modality
Small Molecules
Administration
Oral
01

Overview

Sarpodipil is a pharmaceutical drug used primarily as an oral antiplatelet agent. Its active ingredient is sarpogrelate hydrochloride, which acts as a selective antagonist of the serotonin 5-HT2A receptor. By inhibiting this receptor on platelets and vascular smooth muscle cells, sarpogrelate reduces platelet aggregation and vasoconstriction induced by serotonin, making it useful in the prevention and treatment of thrombotic disorders such as peripheral arterial disease and other conditions where antiplatelet therapy is indicated[3]. The drug has been referenced in Korean pharmaceutical sources under both immediate-release (Tab) and sustained-release (SR Tab) formulations[7]. It has been included in national health insurance reimbursement lists for use as an oral antithrombotic (antiplatelet) agent[3].

Brand names
Sarpodipil TabSarpodipil SR Tab
Other names
사포디필정
02

Targets

HTR2A (Serotonin receptor 5-HT2A)

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