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SARS-CoV-2 convalescent plasma (University Hospital, Geneva)
- Development stage
- Unknown
- Lead developer
- University Hospital
- Administration
- Intravenous
01
Overview
SARS-CoV-2 convalescent plasma is a passive immunotherapy derived from the blood of individuals who have recovered from COVID-19. This plasma contains high titers of neutralizing antibodies (nAbs) specifically targeting the SARS-CoV-2 virus. Developed and studied by the University Hospital, Geneva (HUG), this treatment is intended for early administration in high-risk groups, such as immunocompromised patients and the elderly, to prevent the progression of COVID-19 to severe stages. The mechanism involves the direct neutralization of viral particles, thereby reducing viral load and limiting tissue damage. In the Geneva-led multicentric trial, the plasma used is required to have a neutralizing antibody titer of at least 1:160.
- Other names
- SARS-CoV-2 convalescent plasmaSARS-CoV2 convalescent plasmaSARS-CoV 2 convalescent plasmaCOVID-19 convalescent plasmaCOVID19 convalescent plasmaCOVID 19 convalescent plasma
02
Targets
SARS-CoV-2 spike
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