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SARS-CoV-2 Specific T Cells
- Development stage
- Phase 2
- Modality
- Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
SARS-CoV-2 Specific T Cells are adoptive cell therapy products consisting of T lymphocytes that recognize and target SARS-CoV-2 viral antigens. These cells are typically expanded from convalescent donors or vaccinated individuals and can be used as immunotherapy for COVID-19 patients, particularly those who are immunocompromised or have undergone bone marrow transplantation. The therapy leverages the natural ability of T cells to recognize and eliminate virus-infected cells, potentially providing protection against severe COVID-19 disease.
02
Targets
SARS-CoV-2 spikeSARS-CoV-2 open reading frame 3a protein-derived peptides presented on major histocompatibility complexSARS-CoV-2 N protein MHC-I epitopes (SARS-CoV-2 nucleocapsid protein MHC class I epitopes)pMHC (Peptide-MHC complex family)
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