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SBP-302

Development stage
Preclinical
Lead developer
SML Biopharm
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Intramuscular, Intravenous, Subcutaneous, Intradermal
01

Overview

SBP-302 is an mRNA-based therapeutic candidate developed by SML Biopharm for the treatment of sarcopenia. Part of the company's 'In-vivo Protein Expression Therapeutics' pipeline, SBP-302 utilizes a proprietary lipid nanoparticle (LNP) delivery system to facilitate the intracellular expression of a novel protein target. By leveraging mRNA technology to induce protein production directly within the patient's tissues, the therapy aims to mitigate the muscle mass loss and functional impairment characteristic of sarcopenia. The program is currently in the candidate optimization phase, focusing on refining the mRNA sequence and LNP formulation for optimal protein expression and therapeutic efficacy.

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