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SBT-104 is a preclinical Singh Biotechnology single-domain antibody candidate directed against tumor necrosis factor alpha. The sponsor lists the program as being tested in vivo for rheumatoid arthritis, inflammatory bowel disease, and psoriasis. By inhibiting TNF-alpha, SBT-104 is intended to reduce TNF-driven inflammatory signaling relevant to autoimmune and inflammatory disorders. ([singhbiotechnology.com](https://singhbiotechnology.com/sbt104.html))
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