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SBX-101
- Development stage
- Preclinical
- Lead developer
- Symberix
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
01
Overview
SBX-101 is a preclinical-stage live biotherapeutic product (LBP) developed by Symberix. It is designed as an adjunct therapy to modulate the gut microbiota, specifically targeting the expansion of Proteobacteria. The drug aims to prevent or reduce intestinal toxicities and gastrointestinal side effects associated with the use of anti-neoplastic agents, non-steroidal anti-inflammatory drugs (NSAIDs), and immunosuppressants. By maintaining a healthy microbial balance, SBX-101 is intended to improve the safety profile and tolerability of these primary therapeutic regimens.
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