SC45647

SC45647 is a synthetic guanidine-based sweetener that elicits a sweet taste in both humans and rodents. It is used primarily as an experimental tool in research on the molecular mechanisms of sweet taste perception. SC45647 acts as an agonist of the human sweet taste receptor, specifically targeting the T1R2 + T1R3 heterodimer, which belongs to the class C G protein-coupled receptors (GPCRs). The compound has been utilized as a positive control in studies investigating ligand binding and activation mechanisms of these receptors. Structurally, it belongs to the class of organic compounds known as phenylmethylamines[1][2][5]. There are no known therapeutic or commercial uses for this compound outside laboratory research.

Other names

SC 45647SC45647SC-45647