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"Scaling and chlorhexidine mouthwash" is a standard-of-care clinical intervention used for the treatment of plaque-induced gingivitis and other periodontal diseases. This regimen combines professional dental scaling (a mechanical procedure to remove plaque and calculus from tooth surfaces) with the adjunctive use of chlorhexidine mouthwash, typically at a concentration of 0.12%. Chlorhexidine is a broad-spectrum cationic bisbiguanide antiseptic and antimicrobial agent that targets bacterial cell membranes, disrupting microbial biofilm (dental plaque) formation. In clinical trials, such as those sponsored by Alexandria University, this combination serves as an active comparator arm to evaluate the efficacy of novel herbal mouthwashes (e.g., German chamomile and pomegranate peel extracts) in reducing gingival inflammation and plaque accumulation.
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