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SCB-1019T
- Development stage
- Unknown
- Lead developer
- Clover Biopharmaceuticals
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
SCB-1019T is Clover Biopharmaceuticals' investigational bivalent recombinant protein-subunit vaccine intended to prevent respiratory syncytial virus infection. It contains prefusion-stabilized respiratory syncytial virus fusion glycoprotein antigens representing RSV-A and RSV-B, produced as Trimer-Tag-fused recombinant F-trimer proteins in CHO cells. The vaccine is designed to induce neutralizing antibody responses against both RSV antigenic groups; it has been evaluated in Phase 1 studies in healthy adults, including revaccination of older adults previously vaccinated with AREXVY. ([cdek.pharmacy.purdue.edu](https://cdek.pharmacy.purdue.edu/trial/NCT06843317/))
- Other names
- Bivalent recombinant respiratory syncytial virus vaccine
02
Targets
RSV F (Respiratory syncytial virus fusion protein)
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