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Scrophularia decoction, known in Traditional Chinese Medicine as Xuan Shen Tang, is a herbal preparation primarily derived from the root of *Scrophularia ningpoensis* (Xuan Shen). It is traditionally utilized to "clear heat," "cool blood," and "nourish yin." In modern clinical research, it is frequently studied for its anti-inflammatory and anti-atherosclerotic properties, particularly as a component or variant of the Simiao Yong'an decoction. The formula is investigated for its ability to reduce high-sensitivity C-reactive protein (hsCRP) levels and stabilize atherosclerotic plaques in patients with carotid atherosclerosis. Research conducted by institutions such as Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine has focused on dissecting the specific contributions of Scrophularia within multi-herb regimens to understand its impact on vascular inflammation and endothelial function.
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