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SCT810 is an investigational anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody developed by SinoCelltech for the treatment of moderate-to-severe hemophilia A and hemophilia B, with or without inhibitors. By targeting and blocking TFPI, SCT810 enhances the extrinsic coagulation pathway, thereby promoting hemostasis and rebalancing the coagulation cascade. This factor-independent mechanism of action bypasses the need for coagulation factors VIII or IX, offering a potentially safer, more effective, and more convenient subcutaneous prophylactic treatment option that is unaffected by the presence of inhibitors.
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