Drug intelligence / Profile preview

sctv01c

Development stage
Phase 3
Lead developer
Sinocelltech
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular
01

Overview

SCTV01C is a bivalent recombinant trimeric spike protein subunit vaccine developed by Sinocelltech for the prevention of COVID-19. It targets the spike protein ectodomain sequences of both the Alpha (B.1.1.7) and Beta (B.1.351) SARS-CoV-2 variants, aiming to induce broad immune responses against multiple circulating strains[4][9][10]. The vaccine is administered via intramuscular injection and has been evaluated in clinical trials as a booster for individuals previously vaccinated with mRNA COVID-19 vaccines[3][6]. SCTV01C has demonstrated safety and immunogenicity in healthy adults, with robust cross-neutralizing antibody responses against Delta and Omicron variants following heterologous boosting[6].

02

Targets

BVDV E2 (Bovine viral diarrhea virus glycoprotein E2)SARS-CoV-2 spike

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