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Scutellaria-Coptis granules
- Development stage
- Unknown
- Lead developer
- Beijing Chaoyang Hospital
- Administration
- Oral
01
Overview
Scutellaria-Coptis granules is a Traditional Chinese Medicine (TCM) herbal formulation composed of extracts from *Scutellaria baicalensis* (Huangqin) and *Coptis chinensis* (Huanglian). It is primarily developed and investigated by Beijing Chao-Yang Hospital, affiliated with Capital Medical University, for the treatment of primary hypertension in patients diagnosed with 'heart-and-liver fire' syndrome according to TCM diagnostic criteria. The granules contain bioactive alkaloids and flavonoids, most notably berberine and baicalin, which are thought to exert antihypertensive effects through vasodilation, anti-inflammatory activity, and modulation of the autonomic nervous system. Clinical evaluation focuses on its ability to reduce blood pressure, improve sleep quality, and alleviate TCM-specific symptoms over a short-term treatment period.
- Other names
- Huangqin-Huanglian granulesScutellaria baicalensis and Coptis chinensis granules
02
Targets
iNOS (Nitric oxide synthase, inducible)AMPK (Adenosine monophosphate–activated protein kinase)
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