Drug intelligence / Profile preview

SDTWS01

Development stage
Unknown
Lead developer
Shandong University
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
01

Overview

SDTWS01: sourced facts only. name: "The inhibition constants (Ki) of SDTWS01-04 to PSMA were in the nanomolar range (<10 nM)." [PMID:38823263]; target: "The inhibition constants (Ki) of SDTWS01-04 to PSMA were in the nanomolar range (<10 nM)." [PMID:38823263]; developer: "Key Laboratory for Experimental Teratology of the Ministry of Education and Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China." [PMID:38823263]; modality: "In this study, we developed four new 68Ga-labeled PSMA-targeting tracers by introducing quinoline, phenylalanine and decanoic acid groups to enhance their lipophilicity, strategically limiting their metabolic pathway through the urinary system." [PMID:38823263]

02

Targets

PSMA (Prostate-specific membrane antigen)

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