seasonal influenza vaccine (University Hospitals, Leicester)

The seasonal influenza vaccine associated with University Hospitals, Leicester, refers to the standard non-adjuvanted influenza vaccine used as a comparator or priming agent in clinical research, specifically in studies evaluating heterosubtypic immune responses (NCT00856999). This vaccine typically consists of inactivated influenza virus fragments, providing a total dose of 45 µg of hemagglutinin (standardly 15 µg each for three strains: H1N1, H3N2, and an Influenza B strain). The research conducted by the University Hospitals, Leicester, focused on how prior or concurrent seasonal vaccination affects the immune system's ability to respond to pandemic strains, such as H5N1, particularly in older populations who may exhibit pre-existing cross-reactive antibodies.

Other names

Non-adjuvanted seasonal influenza vaccineSeasonal influenza vaccine